59 Spruce St., Arena District
It's a Columbus landmark, a tourist destination and a bastion for local mom-and-pops. And North Market actually lives up to all that hype. Dating back to 1876, it's become one of the most renowned public markets in the country. With fresh produce stands, butcher counters, ethnic eateries, gift shops and an outdoor farmers market, it really is the best place to buy food in Columbus. Not to mention it's the most fun place to shop - vendors regularly offer up samples of their fare, weekends often feature foodie festivals and the crowd is bustling all year-round.
Runners-up: Whole Foods Market, Weiland's Gourmet Market